Interstate 5

Interstate 5 was a major North-South freeway running through Los Angeles, and the North Valley.

Chaos Theory
It was on the Interstate 5 that Jorge Marquez left his identity behind to become the anarchist Zapata.

Day 1
Jack Bauer told Nina Myers that the location of the Gaines compound was East of the 5, between Tampa and Reseda. He later told Alberta Green that his location was 3 miles north of the split on the 5.

Day 2
The 5 was one of the major LA roads within the blast radius of the nuclear device, according to a presentation by Eric Rayburn.