- World War II takes place during this decade. The United States creates the first atomic bomb in the Manhattan Project, performing the first test detonation at Trinity in June of 1945. (Death Angel)
- Franklin D. Roosevelt serves as President of the United States. (24: The Ultimate Guide)
- The dictator Trujillo holds power in the Dominican Republic during the 1940s. Porfirio Rubirosa works as one of his confidential agents. (Storm Force)
- A movie theater is constructed on Melrose Avenue in Los Angeles, California. The building is later converted into a nightclub, not far from Plush. (Cat's Claw)
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