The prion variant cabal was a group of private military contractors who masterminded the development of the prion variant pathogen in order to destabilize the United States government by launching terror attacks against the US using the pathogen before taking over the security of the country in the form of defense contracts awarded by the government. They provided support for General Benjamin Juma and Colonel Iké Dubaku in exchange for allowing Starkwood to develop the bio-weapon in Sangala.
The most influential member of the cabal, Alan Wilson, was also involved in the Sentox nerve gas conspiracy that took place during Day 5, along with Graem Bauer, Charles Logan, Phillip Bauer and Christopher Henderson. Prior to Day 7, the group's mercenary force was infiltrated by Tony Almeida in an effort to get revenge on Wilson for the death of Michelle Dessler.
During Day 7, there were 13 members of the cabal and they all remained anonymous from each other until Jonas Hodges revealed himself and stole the prion variant for his own purposes. Cara Bowden served as the intermediary between each member.
- Cara Bowden