San Francisco was a city in California, United States. CTU San Francisco is based in the city.
Day 3
During Day 3, a vial of the Cordilla virus was meant to be released in the city.
Day 5
During Day 5, a missile strike from the Natalia was meant to hit the city. Vladimir Bierko stated that he wanted to overlap the targets, because he wanted to make sure there were no survivors.